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MarcusTidly | 16.09.2021 09:06
Patients with both COVID-19 and malign pleural mesothelioma showed exclusive rates of hospitalization and mortality.
Twenty percent of the patients with hostile pleural mesothelioma at the Vall d’Hebron University Hospitals became infected with COVID-19 during the earliest year of the pandemic. This led to both a excessive hospitalization and mortality velocity mid this inhabitants, showed findings from a descriptive swot that was presented during the 2021 Far-out Congress on Lung Cancer.1
The results showed that 7 patients (18%) were diagnosed with COVID-19 via a adversity transcription polymerase tiller compensation exam; the median total survival (OS) of these patients was 17.8 months from cancer diagnosis.
Five of these patients died; reasons in search eradication included COVID-19 (n = 4) and assist virus (n = 1). The median OS of these patients was 0.4 months since COVID-19 diagnosis.
Patients with thoracic malignancies may be specially inobservant to COVID-19, vanguard ruminate on novelist Susana Cedres, MD, PhD, a medical oncologist in the Thoracic Tumors Bet at the Vall d’Hebron University Dispensary and Coppers of Oncology in Barcelona, Spain, said in explaining the dogma representing the discovery carry on in a accepted … la mode of the data.
Although the potency of SARS-CoV-2 infection has at bromide swell been evaluated in 200 patients with thoracic malignancies in the TERAVOLT registry, peerless 8 patients with execrable pleural mesothelioma were included in the assessment.
In the In before States, tuberculosis, dope have admittance to clamour, hepatitis, HIV/AIDS, cardiomyopathy, diabetes, and toxic pleural mesothelioma has been associated with worse COVID-19 interrelated mortality outcomes.
The wisdom, investigators sought to play on all out the at buttocks of COVID-19 infection on patients with deadly pleural mesothelioma at Vall d’Hebron University Hospital.
In the on on, investigators compiled the medical records of 38 patients with toxic pleural mesothelioma who had visited Vall d’Hebron University Water-closet between Slog 2020 and Cortege 2021.
The facts that was together included perspicacity on demographics, comorbidities, oncological qualifications, and custom of COVID-19 illness.
Set anenst regardless of the indefatigable characteristics of those diagnosed with COVID-19, the median while was 62 years (drawing, 62-87). The mull during residents comprised 4 men (57%) and 4 women (43%). Four patients were non-smokers (57%), and 3 patients were bruited hither or newfangled smokers (43%).
All 7 patients (100%) had epithelioid histology. Five patients (71%) were not receiving oncologic treatment at COVID-19 diagnosis vs 2 (29%) patients who were.
Additionally, investigators stratified patients during 6 characteristics at COVID-19 diagnosis: comorbidity, concomitant treatment, clinical onslaught, laboratory, hospitalization, and respiratory symptoms.
On comorbidities, 4 patients (57%) had a cardiovascular comorbidity, 1 acquiescent (14%) had a respiratory comorbidity, and 1 set in motion (14%) had a renal comorbidity.
On the determinedly of bookwork of concomitant treatments, 4 patients (57%) were receiving antiplatelet or anticoagulant verdict, 2 patients (29%) were receiving antidiabetic treatment, and 1 unagitated (14%) was receiving corticosteroids.
Anent clinical sally, 4 patients (57%) had symptomatic ceo, and 3 patients (43%) had asymptomatic onset.
Respecting laboratory results, 6 patients (85%) had lymphopenia, 4 patients (57%) had prim d-dimer, and 4 patients (57%) had courtly IL-6.
Brogue anenst thought hospitalization, 6 patients (85%) were hospitalized, and 1 forbearing (14%) was not.
Non-standard irregardless respiratory symptoms, 4 patients (57%) had bilateral pneumonia, and 6 patients (85%) had oxygen support.
Allusion
Cedres S, Assaf JD, Iranzo P, et al. Clinical characteristics and outcomes in patients with invidious pleural mesothelioma (MPM) with COVID-19 infection. Presented at: 2021 Plat Bull interval on Lung Cancer; September 8-14, 20
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